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Chapter 4Pilot trial Objectives The pilot trial aimed to assess the feasibility of a main trial and to test all trial procedures. Methods Description of trial de This was a pilot, parallel-arm randomised controlled trial with an allocation ratio of 1 test 1, conducted in multi-geographical areas of the UK. Important changes to methods after trial commencement There were no changes to the methods after the trial commenced. Participants Eligibility criteria for participants People aged 16—24 years with a positive chlamydia test result or who had had unsafe sex in the last year defined as more than one partner and at least one occasion of sex without a condom and who owned a mobile phone were eligible. People who satisfied these requirements were ineligible if they were non-English-language speakers or were unable to provide informed consent e. Settings and locations wex the data were collected This trial identified potential participants through sexual health services in six geographical locations in phonee UK: London, Cambridgeshire rural and urbanManchester, East Anglia, Kent and Hull.

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There were some differences in baseline infections and ethnicity between groups. Settings sez locations where the data were collected This trial identified potential participants through sexual health services in six geographical locations in the UK: London, Cambridgeshire rural and urbanManchester, East Anglia, Kent and Hull. Discussion Key findings The pilot trial demonstrated the feasibility of the trial procedures for a main trial.

OM telephoned the referrals and provided detailed verbal information. Data were double entered with one researcher masked to allocation.

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Strengths and weakness In the pilot trial we achieved a high follow-up rate, allocation was concealed and laboratory staff and those analysing data were blind to allocation. Message frequency and spacing For men and women testing positive for chlamydia the intervention included four messages per day for the first 3 days, reducing to one to two messages per day for the first 2 weeks.

Text messages included advice regarding getting tested before unprotected sex with a new partner. Control Control messages were also delivered through the bespoke texting software, that is, numberss the chosen non-embargoed time period. Our response rate may be higher than that achieved by the ClaSS project because our participants had agreed to provide follow-up data when they were recruited, we offered unconditional incentives and we included only essential test kit components.

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Question: Q: Blocking Unsolicited incoming sex messages More Less Apple Footer This site contains user submitted nymbers, comments and opinions and is for informational purposes only. We assessed the s recruited by the randomised during the 3-month time period. There were no changes to the trial outcomes after the trial commenced. online-chess.info Supports Voice Chat, SMS, and MMS messaging directly​. For those diagnosed with an infection, after day 14 the messages targeted condom use and testing for STIs before having unprotected sex with a new partner, employing the same messages as for those who were not diagnosed with an infection.

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We collected embargoed time preference data at enrolment, which were automatically fed into the texting software during baseline data entry see Data collection and entry. If participants had a positive chlamydia or gonorrhoea test result or NSU diagnosis at enrolment, recruiting staff at the clinic entered the baseline data onto the secure online trial database system within 24 hours.

Masking Because of the nature of the intervention, participants could have been aware of their treatment allocation; they would have expected frequent text messages intervention or one text message a month control.

Participants were randomised from 9 September to 29 November and were followed up between October and the end of February The messages were tailored according to sex and infection status at enrolment. Outcomes Primary outcomes The primary outcomes for the pilot trial were the recruitment rates and completeness of follow-up nujbers the proposed primary outcome for the main trial cumulative incidence of STIs at 12 months.

There were three documented cases at 12 months in which participants in the control group reported reading messages sent to other trial participants.

The trial manager OM required access to treatment allocation to monitor the incoming texts and identify intervention participants for the qualitative interviews. We could not reach one participant at the provided. A larger sample size in a main trial would allow for better balance between the arms.

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The messages were deed to provide social support for safer sexual behaviours. The computer automated mode of delivery ensured standardisation of the intervention. Baseline demographic and sexual behaviour characteristics Primary outcomes Our primary outcomes were full recruitment within 3 months and follow-up rate for our proposed primary outcome for the main trial.

All postings and use of the content on this site are subject to the Apple Numbsrs Communities Terms of Use. Data collection and entry We collected self-reported data using the trial baseline and follow-up questionnaires. The Best Sexting Apps For Dirty Texts & Anonymous Nudes For This Trends​Sexting, Like Sex Itself, Is A Consent Minefield For Teen Girls to worry about international calling or texting restrictions — perfect if you meet a.

Laboratory staff assessing chlamydia infection and researchers assessing the outcomes were masked to treatment allocation. links directory. The set of control messages consisted of 13 messages in total, which were spaced 30 days apart starting from the point of randomisation see Numbees 6. Only one of the researchers double entering data was masked to allocation; however, in a main trial there would be sufficient staff for all staff entering follow-up data to be masked to allocation.

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Methods for dealing with missing data We conducted a complete-case analysis only. Over the next week messages targeted numbdrs partner s about an infection.

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It was not deed to generate reliable estimates of the intervention effect and thus the intervention effects are neither accurately estimated nor generalisable. Staff performing the statistical analysis were also masked to treatment allocation. There was no differential follow-up between groups.

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The of messages was then reduced to one per day for the first month followed by between one and nine per month until 12 months. Participant views of the intervention suggest that it is acceptable to the majority of participants.

Generalisability The pilot trial was deed to demonstrate the feasibility of a njmbers trial. Time points for analysis This is a behavioural intervention unlikely to produce adverse effects and so the analysis by the research team was undertaken once, at the end of the trial and after the data set had been locked. We report the cumulative incidence rate of chlamydia infection in the control group to inform the sample size calculation for the main trial.

Allocation concealment The online randomisation system generated the allocation sequence, which meant that staff enrolling participants into the trial could not have known in advance which treatment allocation the next participant would receive. Sample size The aim of the pilot trial was to estimate the likely rate of recruitment and rate of follow-up at 12 months to assess the feasibility of the main trial.

As this was a behavioural intervention unlikely to cause harm there were no stopping rules. Maximum 3 replies per text.

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Alexis Fawx is on SextPanther! Taking part in the texting study can help things to be equal. Call, Text and Share Nude Pics with Alexis Fawx now! Implementation The online randomisation system randomised participants immediately after the recruiting staff entered their baseline data onto the test trial database system see Recruitment and Data collection and entry. For shorter non-embargoed periods, the system delivered the messages in proportionally shorter intervals.

Recruitment staff on site assessed potential participants for eligibility, provided detailed verbal and written information and gave potential participants the opportunity to ask any questions. We analysed by randomised arm and phlne a complete case analysis only.